- Written by Dimitar Kirkovski
Martina Savova, MSc in Pharmacy
Position: Laboratory manager / Technician
Department: Plant Cell Biotechnology, CPSBB
The main area of Martina’s research interests is modulation of obesity mechanisms through plant extracts and bioactive phytochemicals using in vitro model of human SGBS adipocytes.
Martina is also interested in NMR-based metabolomics, bioactivity of plant-derived secondary metabolites and pharmacological modulation with natural compounds of the transcription factor Nrf2 in different in vitro models.
Georgiev M.I., Vasileva L.V., Savova M.S. (2021) Antiobesity molecules of natural origin: Call for lead finding acceleration. Food Frontiers. DOI: 10.1002/fft2.59.
Savova M.S., Vasileva L.V., Mladenova S.G., Amirova K.M., Ferrante C., Orlando G., Wabitsch M., Georgiev M.I. (2021) Ziziphus jujuba Mill. leaf extract restrains adipogenesis by targeting PI3K/AKT signaling pathway. Biomedicine and Pharmacotherapy. (accepted). (IF 6.529).
Vasileva L.V., Savova M.S., Tews D., Wabitsch M., Georgiev M.I. (2021) Rosmarinic acid attenuates obesity and obesity-related inflammation in human adipocytes. Food and Chemical Toxicology. 149: 112202. (IF 4.679)
Vasileva L., Savova M., Amirova K., Balcheva-Sivenova Zh., Ferrante C., Orlando G., Wabitsch M. , Georgiev M.I. (2020) Caffeic and chlorogenic acids synergistically activate browning
program in human adipocytes: Implications of AMPK and PPAR-mediated Pathways. International Journal of Molecular Sciences. 21: 9740. (IF 4.556)
Vasileva L., Savova M., Amirova K., Dinkova-Kostova A., Georgiev M.I. (2020) Obesity and NRF2-mediated cytoprotection: Where is the missing link? Pharmacological Research. 156: 104760. (IF 5.893)